FUNDED PROJECTS:
NEUROLOGICAL DISEASES

cartell MaratóFollowing the 1996 edition, which was dedicated to neurological diseases, the sum of €3,677,019 was distributed among the 37 biomedical researh projects listed below and used to support research on these diseases. The results were published in the III Simposium Fundació La Marató de TV3, which took place in 2002.
Below is a list of the projects financed by La Marató in 1996. Those that led to the production of scientific literature are underlined.

Study on Alzheimer's Disease in Primary Care: Follow-Up of a Host of People over 65 and Evaluation of the Effectiveness of Support Intervention for the Primary Carers of these Patients

  • Dr. Josep M. Argimon Pallàs
    Fundació Jordi Gol i Gurina
Fund: 34.763 €

JC Virus and Glial Cells: Study of Deregulation of the Cell Cycle in Progressive Multifocal Leuko-Encephalopathy

  • Dr. Aurelio Ariza Fernández
    Hospital Universitari Germans Trias i Pujol
Fund: 63.707 €

Role of Adamalycins in Generating the Abeta Peptide

  • Dr. Joaquín Arribas López
    Hospital General Universitari Vall d'Hebron
Fund: 94.240 €

Design, Synthesis and Pharmacological Evaluation of Analogues of Huperzina A as Anti-Cholinesterase with Potential Use in Treating Alzheimer's Disease

  • Dr. Pelayo Camps García
    Facultat de Farmacia. Universitat de Barcelona
  • Dr. Albert Badia Sancho
    Facultat de Medicina. Universitat Autònoma de Barcelona
  • Dr. Francisco Javier Luque Garriga
    Facultat de Farmàcia. Universitat Autònoma de Barcelona
Fund: 143.341 €

Can Glial Cells Determine Survival or Neuron Death during Evolution of Neuro-Degenerative Processes?

  • Dr. Bernardo Castellano López
    Facultat de Medicina. Universitat Autònoma de Barcelona
Fund: 110.088,59 €

Genetic and Physio-Pathological Neuro-Pathological Correlations in Alzheimer's Disease: Characterization of a Peripheral Model for Diagnosis and Experimental Handling of the Disease

  • Dr. Félix Francisco Cruz-Sánchez
    Universitat Internacional de Catalunya
  • Dra. Arantxa Ortega Aznar
    Hospital General Universitari Vall d'Hebron
  • Dr. José Luis Mate Sanz
    Hospital Universitari Germans Trias i Pujol
Fund: 319.726 €

Excitotoxic Mechanisms in the Spinal Motoneuron and Its Implications in the Pathogeny of Amyotrophic Lateral Sclerosis

  • Dr. Josep-Enric Esquerda Colell
    Facultat de Medicina. Universitat de Lleida
Fund: 139.718 €

Involvement of Apoptosis Proteins, Calcium-Binding Proteins and Trophic Factors in Human Neuro-Degenerative Diseases and in Experimental in vivo and in vitro Models

  • Dr. Isidre Ferrer Abizanda
    Ciutat Sanitària i Universitària de Bellvitge
Fund: 81.055 €

AnàlisiImmuno-Histologic and Genetic Clinical Analysis of Dystrophy of the Waist

  • Dra. Maria Pia Gallano Petit
    Hospital de la Santa Creu i Sant Pau
Fund: 50.317 €

Effect of Inflammatory Cytokines on the Cyclical Nitric Oxide /GMP System of Nerve Cells in Relation to Multiple Sclerosis and Alzheimer's Disease

  • Dra. M. C. Agustina García Sánchez
    Institut de Biologia Fonamental Vicent Villar i Palasí. Universitat Autònoma de Barcelona
Fund: 77.350 €

Prospective Neuro-Psychological Neuro-Physical and Spectroscopic Study of Early Markers of Alzheimer's Disease

  • Dra. Carmen García Sánchez
    Hospital de la Santa Creu i Sant Pau
Fund: 65.253 €

Specificity and Pathogenic Value of Glucolipidic Antigens in Motor Neurons: Relevance in ALS and Other Motor Syndromes

  • Dr. Josep Maria Grau Veciana
    Hospital de la Santa Creu i Sant Pau
  • Dra. Francisca Vidal Domínguez
    Facultat de Veterinària. Universitat Autònoma de Barcelona
  • Dr. Nicolau Ortiz Castellon
    Facultat de Medicina. Universitat Rovira i Virgili
Fund: 297.987 €

Multiple Sclerosis and Paraneoplastic Encephalomyelitis

  • Dr. Francesc Graus Ribas
    Hospital Clínic i Provincial de Barcelona
Fund: 161.732 €

Study and Characterization of Specific T anti-GAD Cells in Patients with Auto-Immune Cerebellar Ataxia and Stiff-Man Syndrome. Comparison with Insulin-Dependent Diabetes Mellitus

  • Dra. Dolores Jaraquemada Pérez de Guzman
    Facultat de Medicina. Universitat Autònoma de Barcelona
Fund: 85.428 €

Evaluation of the Efficiency, Safety and Effectiveness of Multiple Sclerosis Treatment and Impacts on the Quality of Life of Patients and their Relatives

  • Dr. Albert J. Jovell Fernández
    Agència d'Avaluació de Tecnologia i Recerca Mediques
Fund: 57.570 €

Longitudinal Study of the Functional Reorganization of Frontal Basal Ganglion Circuits Following Pallidotomy or Posteroventral Pallial Electric Stimulation Guided by Microregister for Surgical Treatment

  • Dr. Jaume Kulisevsky Bojarski
    Hospital de la Santa Creu i Sant Pau
Fund: 60.339 €

Depressive Disorders in Patients Affected by Essential Thrombocythemia. Study of the Possible Serotoninergic Mechanisms Involved

  • Dr. Miquel Marco Igual / Dr. Josep Mª Ribera Santasusana
    Consorci Hospitalari Parc Taulí. Sabadell / Hospital Universitari Germans Trias i Pujol
Fund: 46.452 €

Comparative Analysis of the Pathogeny of Leucoaraiosis between Binswanger's Disease and Alzheimer's Disease: Haemodynamic Haemorrheological Studies of Conventional and Spectroscopic Magnetic Resonance

  • Dr. Joan Martí Fàbregas
    Hospital de la Santa Creu i Sant Pau
Fund: 53.950 €

Interactions among Glutamate, Dopamine, Polyamines and Adenosine in Neuro-Degenerative Processes. An Experimental Approach to Parkinson's Disease

  • Dr. Emili Martínez Hermida
    Institut d'Investigacions Biomèdiques de Barcelona. CSIC
Fund: 59.095 €

Inflammatory Mechanisms in the Pathogenesis of Alzheimer's Disease: Study of the Role of Phosphodiesterases

  • Dra. Guadalupe Mengod Los Arcos
    Instituto de Investigaciones Biomédicas de Barcelona. CSIC
Fund: 162.273 €

Identification and Study Using Combinatorial Libraries of New Therapeutic Agents Related to Inhibiting Acetyl-Cholinesterase and to the Neuro-Toxicity of Glutamate

  • Dr. Àngel Messeguer Peipoch
    Centre d'Investigació i Desenvolupament. CSIC
  • Dr. Vicente Felipo Orts
    Institut d'Investigacions Citològiques. Fundació Valenciana d'Investigacions Biomèdiques
Fund: 162.273 €

Role of the Proteolytic Enzyme tPA in Neuron Migration during the Development of the Cerebellum in Mice with tPA deficiencies (tPA -/-). Transcriptional Regulation of the tPA by Thyroid Hormone in the Central Nervous System

  • Dra. Pura Muñoz Cánoves
    Institut d'Investigació Oncològica
Fund: 115.220 €

Is There a Correlation between Mutations in the +Subunits of Complexes of the Respiratory Chain Coded by Mitochondrial DNA (mtDNA) and its Enzyme Activity in Patients Suffering from Alzheimer's Disease?

  • Dra. Virginia Nunes Martínez
    Centre de Genètica Mèdica i Molecular. Institut d'Investigació Oncològica
  • Dr. Jordi Casademont Pou
    Hospital Clínic i Provincial de Barcelona
Fund: 124.019 €

Computer-Assisted Design of Selective Agonists and Antagonists of Muscarinic Receptors as Treatment for Alzheimer's Disease

  • Dr. Leonardo Pardo Carrasco
    Facultat de Medicina. Universitat Autònoma de Barcelona
Fund: 86.527 €

Circuits of the Rat and Human Cerebral Cortex that are Rich in Zinc: A Group of Glutamatergic Circuits with Possible Involvement in Epilepsy

  • Dr. Jeús Pérez Clausell
    Facultat de Biologia. Universitat de Barcelona
Fund: 49.509 €

Recording and Analysis of Data on Amyotrophic Lateral Sclerosis (ALS) in Catalonia

  • Dr. Jesús Pradas Orozco
    Hospital de la Santa Creu i Sant Pau
Fund: 43.002 €

Quantification of Selectivity in Re-Innervation of the Proximal and Distal Muscles of the Lower Extremity Following Lesion of the Sciatic Nerve

  • Dr. Alberto Prats Galino
    Facultat de Medicina. Universitat de Barcelona
Fund: 23.638 €

Opiated Endogenous System: Modulation Inhibiting Sensory Transmission during Peripheral Inflammation

  • Dra. Margarita Puig Riera de Conías
    Institut Municipal d'Investigació Mèdica
  • Dra. Eulalia Planas Domingo
    Facultat d'Odontologia. Universitat de Barcelona
Fund: 144.243 €

Involvement of Central Tolerance in Auto-Immune Neurological Diseases

  • Dr. Ricardo Pujol Borrell
    Hospital Universitari Germans Trias i Pujol
Fund: 111.033 €

Study of the Alterations of Cerebral Blood Flow and Tissue Oxygenation in Patients Having Severe Cranial-Encephalic Trauma and Diffused Post-Traumatic Lesions

  • Dr. Joan Sahuquillo Barris
    Hospital de Traumatologia Vall d'Hebron
Fund: 40.530 €

Schizophrenia and Serotoninergic System. Therapeutic Implications

  • Dr. Lluís San Molina
    Benito Menni Complex Assistencial en Salut Mental. Sant Boi de Llobregat
Fund: 12.568 €

Potential of the Netrina 1/DCC Signalling System in Regenerating CNS

  • Dr. Eduard Soriano García
    Facultat de Biología. Universitat de Barcelona
  • Dra. Myriam Fabre
    Institut Municipal d'Investigació Mèdica
Fund: 144.243 €

Study of the Mechanisms of Neuron Death in the Black Matter Induced by the Destruction of Striated Deopaminergic Terminals. Neuro-Protection Role of Trophic Factors and Glutamatergic Antagonists in this Experimental Model of Parkinson's Disease

  • Dr. Eduard Tolosa Sarró
    Hospital Clínic i Provincial de Barcelona
Fund: 149.913 €

Role of Calmoduline,Calmoduline Kinase-2 and Calcineurine in Neuro-Degenerative Process Related to Alzheimer's Disease

  • Dr. Josep M. Tusell Puigbert
    Institut d'Investigacions Biomèdiques de Barcelona. CSIC
Fund: 116.945 €

Stimulating Cognitive Functions and its Repercussion in the Psycho-Social Adaptation Process in Multiple Sclerosis: Applications of Computer Technology in this Field

  • Dr. Josep M. Vendrell Brucet
    Hospital de Dia de la Fundació Esclerosi Múltiple
Fund: 50.472 €

Preventing Relapses, Hospital Admissions and Suicidal Behavior in Manic-Depressive Psychosis by Means of Psycho-Educational Techniques and Pharmacological Treatment

  • Dr. Eduard Vieta Pascual
    Hospital Clínic i Provincial de Barcelona
Fund: 37.820 €

Cognitive Rehabilitation Program for Patients with Alzheimer-type Senile Dementia

  • Dr. Joan Vilalta Franch
    Hospital de Santa Caterina. Girona
Fund: 40.576 €
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