FUNDED PROJECTS:
CARDIOVASCULAR DISEASES

cartell MaratóIn the 2007 Marató, which dealt with cardiovascular diseases, 159 projects were presented and these were assessed by 145 scientists specialising in these diseases, according to their quality, methodology and relevance. This assessment was managed by the Catalan Agency for Health Technology Assessment and Research, of the Catalan Ministry of Health.
In accordance with the proposal of the scientific Advisory Committee of the Fundació La Marató de TV3, the Board agreed to distribute € 7.025.236 to the following 26 research projects of excellence:

Vascular events in noncardiac surgery patIents Cohort evaluation study. The VISION study

  • Dr. Pablo Alonso Coello
    Hospital de la Santa Creu i Sant Pau
  • Dr. Ignacio Garutti Martínez
    Hospital General Universitario Gregorio Marañón. Madrid
Fund: 292.378 €

Drug discovery targeted at transthyretin cardiac amyloidosis

  • Dra. Gemma Arsequell Ruiz
    Institut d'Investigacions Químiques i Ambientals de Barcelona
  • Dr. Antoni Planas Sauter
    Institut Químic de Sarrià URL
  • Dr. Jordi Ramon Quintana Ruiz
    Parc Científic de Barcelona
Fund: 489.000 €

Analysis of the fibrotic process associated with cardiac ventricular remodelling in patients with heart failure

  • Dra. Montserrat Batlle Perales
    Institut d'Investigacions Biomèdiques August Pi i Sunyer
Fund: 199.882,74 €

Development of biological scaffolds for post-infarction scar repair: local delivery of stem cells, angiogenic factors and on-line monitoring of myocardial regeneration

  • Dr. Antoni Bayés Genís
    Hospital Universitari Germans Trias i Pujol
  • Dr. Ramon Bragós Bardia
    Escola Tècnica Superior d'Enginyeria de Telecomunicacions UPC
  • Dr. Carlos Eduardo Semino
    Institut Químic de Sarrià URL
Fund: 481.298 €

Predictors of right ventricular positive remodelling after pulmonary valve replacement in adult patients with repaired tetralogy of Fallot and long standing pulmonary regurgitation

  • Dr. Jaume Casaldàliga Ferrer
    Institut de Recerca - Hospital Universitari Vall d'Hebron
Fund: 80.750 €

Electrophysiological and molecular characterization of cardiac repolarization in the isolated human heart

  • Dr. Juan M. Cinca Cuscullola
    Hospital de la Santa Creu i Sant Pau
  • Dr. Francisco Javier Chorro Gasco
    Hospital Clínic Universitari de València
  • Dr. Rubén Coronel
    Academic Medical Center - Amsterdam
Fund: 304.242,50 €

Studying the molecular bases of tissue injury and repair after myocardial infarction: role of the complement system

  • Dra. Cristina Costa Vallès
    Institut d'Investigació Biomèdica de Bellvitge
  • Dra. Roser López Alemany
    Hospital Duran i Reynals
  • Dra. Stéphanie Barrère-Lemaire
    Institut de Génomique Fonctionnelle. Montpellier
Fund: 289.572,50 €

Genetic susceptibility to coronary neovascularisation in patients with coronary heart disease: an approach based on single nucleotide polymorphism genotyping of genes involved in arteriogenesis and angiogenesis

  • Dr. Josep Maria de Anta Vinyals
    Facultat de Medicina CSUB
Fund: 95.715 €

Identification of genetic variants for essential hypertension by genome-wide association

  • Dr. Roberto Elosua Llanos
    Institut Hospital del Mar d'Investigacions Mèdiques
Fund: 197.773 €

Ras/MAPK signalling regulates cholesterol efflux

  • Dr. Carlos Enrich Bastús
    Facultat de Medicina UB
Fund: 198.125 €

Regulation of angiogenesis in portal hypertension. Evaluation of new therapeutic strategies

  • Dra. Mercedes Fernández Lobato
    Institut d'Investigacions Biomèdiques August Pi i Sunyer
Fund: 118.497,50 €

Thrombus stabilization as therapeutic target: from in vitro studies to animal models

  • Dr. Pablo García de Frutos
    Institut d'Investigacions Biomèdiques de Barcelona
  • Dr. Pablo Fuentes Prior
    Hospital de la Santa Creu i Sant Pau
Fund: 291.125 €

Intercellular signalling in aortic valve development and homeostasis

  • Dr. Antonio García de Herreros Madueño
    Institut Hospital del Mar d'Investigacions Mèdiques
  • Dr. José Luis de la Pompa Mínguez
    Centro Nacional de Investigación Cardiovascular Carlos III
Fund: 350.000 €

Perivascular adipocytes and signalling trough toll-like receptors: Role in the pathophysiology of atherosclerosis

  • Dr. José Miguel González Clemente
    Hospital de Sabadell
Fund: 130.920,81 €

Perivascular Adipocytes and Signaling trough Toll-like Receptors: Role in the Pathophysiology of Atherosclerosis

  • Dr. Cándido Juárez Rubio
    Hospital de la Santa Creu i Sant Pau
Fund: 198.125 €

Intracellular signal pathways involved in modulation of low density lipoprotein receptor-related protein (LRP1) expression by hypercholesterolemia and hypertension. Consequences for vascular cell and cardiomyocyte activity. Implications in cardiovascular pathophysiology

  • Dra. Concepción Vicenta Llorente Cortés
    Institut Català de Ciències Cardiovasculars
Fund: 197.999 €

Calcineurin and NFAT proteins in cardiac hypertrophy and inflammation-induced myocardial dysfunction

  • Dra. Cristina López Rodríguez
    Facultat de Ciències de la Salut i de la Vida UPF
  • Dr. Juan Miguel Redondo Moya
    Centro Nacional de Investigaciones Cardiovasculares Carlos III
Fund: 349.995 €

Life-style and environmental determinants of cardiovascular diseases in a Spanish cohort study

  • Dr. Jaume Marrugat de la Iglesia
    Hospital del Mar. IMIM
  • Dr. Joan Sala Montero
    Hospital Universitari Doctor Josep Trueta. Girona
  • Dr. Xavier Basagaña Flores
    Centre de Recerca en Epidemiologia Ambiental
Fund: 499.879 €

Molecular mechanisms of endothelial progenitor cell differentiation during endothelium repair in pulmonary hypertension

  • Dr. Víctor Ivo Peinado Cabré
    Hospital Clínic i Provincial de Barcelona
Fund: 195.725,63 €

Unique domains of src family kinases involved in cardiovascular diseases

  • Dr. Miquel Pons Vallès
    Institut de Recerca Biomèdica de Barcelona
Fund: 199.375 €

Kawasaki Disease: Disentangling the role of climate in the outbreaks

  • Dr. Xavier Rodó López
    Institut Català de Ciències del Clima
Fund: 196.250 €

Chronic total occlusions of human coronary arteries: from pathophysiology to long-term clinical implications of successful recanalization by means of percutaneous coronary intervention

  • Dr. Manel Sabaté Tenas
    Hospital Clínic i Provincial de Barcelona
  • Dra. Petia Radeva
    Centre de Visió per Computador UAB
  • Dra. Rosana Hernández Antolín
    Hospital Clínico San Carlos. Madrid
Fund: 327.680 €

Opti-heart: Optimising 3D imaging to characterise normal and defective heart development

  • Dr. James Sharpe
    Centre de Regulació Genòmica
  • Dr. Juan José Sanz Ezquerro
    Centro Nacional de Investigaciones Cardiovasculares Carlos III
Fund: 346.590 €

Molecular mechanisms involved in lxr-and rxr-mediated prevention of a atherosclerosis

  • Dra. Annabel Valledor Fernández
    Facultat de Biologia UB
  • Dra. Mercedes Ricote Pacheco
    Centro Nacional de Investigaciones Cardiovasculares Carlos III
  • Dra. Maria Rosa Sarrias Fornés
    Hospital Universitari Germans Trias i Pujol
Fund: 497.873,22 €

Ion channels in the pathogenesis and pharmacological response of essential hypertension

  • Dr. Miguel Ángel Valverde de Castro
    Facultat de Ciències de la Salut i de la Vida UPF
  • Dr. Mariano Sentí Clapés
    Institut Hospital del Mar d'Investigacions Mèdiques
Fund: 297.326,25 €

Implication of estrogen-related receptors in the etiology of diabetic cardiomyopathy: role as potential pharmacological targets for the treatment of diabetic cardiomyopathy

  • Dr. Josep Antoni Villena Delgado
    Institut de Recerca de Hospital Universitari Vall d'Hebron
Fund: 199.138 €
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