FUNDED PROJECTS:
AIDS

cartell MaratóIn 2001 the Marathon, which was dedicated to Aids, received 107 project applications; these were evaluated by 49 scientists specialising in HIV around the world who drew up an order of priority depending on the methodological quality and relevance of the project. The assessment was managed by the Catalan Agency for Health Technology Assessment and Research.
In accordance with the proposal from the Advisory Committee of the Fundació La Marató de TV3, the Board agreed to distribute, after paying the costs of the evaluation, € 3,910,600 to 21 biomedical research projects. The results were published in the VIII Simposium Fundació La Marató de TV3, which took place in 2007.

State epidemiological information system on non-occupational HIV post-exposure prophylaxis. Study of viability and effectiveness of post-exposure prophylaxis in the non-health field

  • Dr. Jesús Almeda Ortega
    Hospital Universitari Germans Trias i Pujol
Fund: 146.686 €

Epidemiological quantification and characterisation of HIV seroconversors using the Serological Testing Algorithm for Recent HIV Seroconversion (STARHS) technique.

  • Dr. Jordi Casabona Barbarà
    Hospital Universitari Germans Trias i Pujol
Fund: 176.088 €

Entry of the immunodeficiency virus to the target cell and physiochemical characteristics of the cell membrane: importance of the dipolar membrane potential and of the proteglycans of the cell surface

  • Dr. Josep B. Cladera Cerdà
    Facultat de Medicina / UAB
Fund: 90.457 €

Analysis of the prevalence of HIV resistant to antiretrovirals and subtypes in patients with no previous experience of antiviral treatment in Spain

  • Dr. Bonaventura Clotet Sala
    Hospital Universitari Germans Trias i Pujol
  • Dr. Santiago Moreno Guillen
    Hospital Ramon y Cajal / Madrid
  • Dr. Vicente Soriano Vázquez
    Instituto de Salud Carlos III / Madrid
  • Dra. Nuria Margall Coscojuela
    Hospital de la Santa Creu i Sant Pau
  • Dra. Asunción Moreno Camacho
    Hospital Clínic i Provincial de Barcelona
Fund: 193.229 €

Redirection of T-cells specificity against HIV epitopes restricted by HLA-A2 using gene transfer

  • Dr. Oscar de la Calle Martin
    Hospital de la Santa Creu i Sant Pau
Fund: 166.120 €

Molecular bases of lipodystrophy associated with high-activity antiretroviral therapy in Aids patients: a genomic approach

  • Dr. Pere Domingo Pedrol
    Facultat de Medicina / UAB
  • Dra. Marta Giralt Oms
    Facultat de Biologia / UB
Fund: 176.000 €

Design, synthesis, and evaluation of the antiviral activity of new anti-HIV compounds

  • Dr. José Andrés Esté Araque
    Fundació irsiCaixa / HUGTiP
  • Dr. Jordi Teixidó Closa
    Grup d'Enginyeria Molecular / IQS
  • Dra. Josefa Mallol Montero
    Facultat de Química / UB
Fund: 309.336 €

Genetic variability of the locus of the vitamin D receptor (VDR) and progression of HIV infection. Study of new variants and characterisation of the molecular base of the differential progression to Aids conferred by VDR polymorphisms

  • Dr. Joan Fibla Palazón
    Facultat de Medicina / UdL
  • Dra. Montserrat Plana Prades
    Hospital Clínic i Provincial de Barcelona
  • Dr. Antonio José Caruz Arcos
    Facultad de Ciencias Experimentales / UJ
  • Dr. Benito Regueiro Garcia
    Universidad de Santiago / Sergas
Fund: 359.191 €

The role of CXCR4/CD26 heteromers in the T-lymphocyte functionality and in the entry and infectiveness of HIV.

  • Dr. Rafael Franco Fernández
    Facultat de Química / UB
Fund: 180.028 €

Use of autologous myeloid dendrite cells as a cellular adjuvant for a therapeutic vaccine against the type-1 immunodeficiency virus (HIV-1) in infected patients in primary stages of the disease receiving high-activity antiretroviral treatment

  • Dr. Josep M. Gatell Artigas
    Hospital Clínic i Provincial de Barcelona
Fund: 169.560 €

Polymorphic receptors of the innate immune system (MBL, TLR) and susceptibility to bacterial infections in patients infected by HIV: a study of cases and controls

  • Dr. Juan Pablo Horcajada Gallego
    Hospital Clínic i Provincial de Barcelona
Fund: 111.600 €

Lethal mutagenesis, a new antiviral strategy

  • Dr. Miguel Angel Martínez de la Sierra
    Fundació irsiCaixa / HUGTiP
Fund: 154.349 €

Molecular and cellular immunity in identical twins, infected by the same stem of the human immunodeficiency virus (HIV-1)

  • Dr. Xavier Martínez Picado
    Hospital Universitari Germans Trias i Pujol
Fund: 147.124 €

Phenotype and molecular characterisation of the non-Hodgkin's lymphomas associated with Aids using tissue microarray techniques

  • Dr. José Luis Mate Sanz
    Hospital Universitari Germans Trias i Pujol
Fund: 174.118 €

Analysis of the function of the mitochondrial respiratory chain in patients infected by HIV who develop hyperlactataemia during antiretroviral treatment

  • Dr. Òscar Miró Andreu
    Hospital Clínic i Provincial de Barcelona
Fund: 82.080 €

Long-term consequences of hepatitis C and B in intravenous drug addicts infected by HIV

  • Dr. Robert Muga Bustamante
    Hospital Universitari Germans Trias i Pujol
  • Dr. Ildefonso Hernández Aguado
    Facultad de Medicina / UMH
Fund: 179.486 €

Inhibitor effect of the urokinase-receptor system in HIV-1 replication: in vitro and in vivo study

  • Dra. Pura Muñoz Cánoves
    Centre de Regulació Genòmica
  • Dr. Guido Poli
    Hospital San Raffaele Scientific Institute / Milano
  • Dr. Francesco Blasi
    Faculty of Medicine / Milano
Fund: 359.772 €

Invasive pneumococcal disease in patients infected by the of human immunodeficiency virus. Multi-centre study of three European hospitals

  • Dr. Romà Pallarés Giner
    Ciutat Sanitària i Universitària de Bellvitge
Fund: 179.099 €

Regulatory mechanisms of adipogenesis to HIV-associated lipodystrophy

  • Dr. Cristóbal Richart Jurado
    Hospital Universitari Joan XXIII / Tarragona
Fund: 99.907 €

Identification of the cell factors that interact with the Vif protein of the acquired immunodeficiency virus

  • Dr. Juan Sayós Ortega
    Facultat de Ciències de la Salut i de la Vida / UPF
Fund: 142.549 €

Polymorphism of rant and SDF-1 chemokines and their influence on virological response and immunological recovery due to antiretroviral treatment in patients infected by HIV.

  • Dr. Francesc Vidal Marsal
    Facultat de Medicina / URV
  • Dr. Hernando Knobel Freud
    Hospital del Mar
  • Dr. Juan Antonio Arroyo Díaz
    Hospital de la Santa Creu i Sant Pau
  • Dr. Santiago Montull Morer
    Hospital General de Granollers
  • Dr. David Dalmau Juanola
    Hospital Mútua de Terrassa
Fund: 313.821 €
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