FUNDED PROJECTS:
INFECTIOUS DISEASES

cartell MaratóIn the 2017 Marató, which dealt with infectious diseases, 214 projects were presented and these were assessed by 103 scientists specialising in these diseases, according to their quality, methodology and relevance. This assessment was managed by the Agency for Health Quality and Assessment of Catalonia, of the Catalan Ministry of Health. In accordance with the proposal of the scientific Advisory Committee of the Fundació La Marató de TV3, the Board agreed to distribute €8.302.384 to the following 36 research projects of excellence:

Impact of the early detection of resistances to antimicrobials in the reduction of inadequate treatments in bacteraemia caused by enterobacteria.

  • Dra. Mónica Ballestero Téllez
    CatLab - Parc Logístic de Salut
Fund: 87.527,50 €

Respiratory syncytial virus (RSV) in pregnant women and children from sub-Saharan Africa: determination of the incidence of the disease, associated mortality and risk factors.

  • Dra. Azucena Bardají Alonso
    Institut de Salut Global de Barcelona - ISGLOBAL
  • Dr. Nelson del Rosário Tembe
    Centro de Investigaçao em Saúde de Manhiça Fundaçao Manhiça. Moçambic
Fund: 278.995,05 €

Selective recognition of non-coding RNA and search for new therapeutic targets to combat antibiotic-resistant bacterial infections.

  • Dra. Ester Boix Borràs
    Facultat de Biociències. Universitat Autònoma de Barcelona
Fund: 195.000,00 €

Optimisation of antibiotic prescription in acute uncomplicated infections of the respiratory tract in children: controlled randomised multicentre clinical trial with 2x2 factorial design.

  • Dr. Ignasi Bolíbar Ribas
    Institut d’Investigacions Biomèdiques Hospital de la Santa Creu i Sant Pau
Fund: 199.648,13 €

Development of new functional nanoparticles aimed at the lymph node for elimination of latent HIV reservoir.

  • Dra. Maria J. Buzón Gómez
    Institut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: 199.998,75 €

Immunotherapy against the ESKAPE pathogens based on the bacterial proteins of iron capture.

  • Dra. Susana Campoy Sánchez
    Facultat de Biociències. Universitat Autònoma de Barcelona
Fund: 180.018,75 €

Identification of biomarkers based on the energy metabolism and oxidative stress in patients with catheter-associated urinary infections and development of biosensors for determination.

  • Dr. Jordi Camps Andreu
    Institut d'Investigació Sanitària Pere Virgili - IISPV
Fund: 197.500,00 €

Impact of integral molecular tests to reduce antibiotic use in pneumonia acquired in the community: random controlled trial.

  • Dr. Jordi Carratalà Fernández
    Institut d'Investigació Biomèdica de Bellvitge - IDIBELL
Fund: 199.974,23 €

Impact of loss in clinical follow-up and ageing in the population infected by HIV in Catalonia and the Balearic Islands: population-based cohort study.

  • Dr. Jordi Casabona Barbarà
    Agència de Salut Pública de Catalunya - Institut d'Investigació Germans Trias i Pujol
  • Dr. Arkaitz Imaz Vacas
    Institut d'Investigació Biomèdica de Bellvitge - IDIBELL
Fund: 271.590,00 €

Extracellular vesicles as a new prognostic biomarker for Chagas disease, a chronic infection emerging in Catalonia.

  • Dra. M. del Carmen Fernández Becerra
    Institut de Salut Global de Barcelona - ISGLOBAL
Fund: 184.375,00 €

Coated liposomal nanocomplexes as drug release systems for the treatment of leishmaniasis.

  • Dr. Xavier Fernández Busquets
    Centre Esther Koplowitz CEK- Institut de Bioenginyeria de Catalunya
  • Dra. Maria Manconi
    Facoltà di Biologia e Farmacia. Università degli Studi di Cagliari. Itàlia
  • Dra. Maria Cristina Riera Lizandra
    Facultat de Farmàcia i Ciències de l'Alimentació. Universitat de Barcelona
Fund: 399.480,85 €

Prevention of infections related to vascular catheters through the functionalisation of catheters impregnated with heat-activatable hydrogels with wide spectrum antimicrobials (FUNCATH).

  • Dr. Oriol Gasch Blasi
    Consorci Hospitalari del Parc Taulí
  • Dra. Cristina Garcia de la Maria
    Hospital Clínic i Provincial de Barcelona - Fundació Clínic per a la Recerca Biomèdica
  • Dra. Imma Ratera Bastardas
    Institut de Ciència de Materials de Barcelona ICMBA - CSIC
  • Dra. Elena Garcia Fruitós
    Institut de Recerca i Tecnologia Agroalimentàries - IRTA
Fund: 375.078,75 €

ThermoShots. A new non-existent technology for prevention and treatment of antimicrobial resistance (AMR) and infections associated with biofilms of medical devices.

  • Dr. Joan Gavaldà Santapau
    Institut de Recerca Hospital Universitari Vall d'Hebron -VHIR
Fund: 199.000,00 €

New prevention strategies against STI/HIV acquisition through elimination of the myeloid-derived suppressor cells.

  • Dra. Meritxell Genescà Ferrer
    Institut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: 199.685,00 €

Challenging the periodontal pathogen Porphyromonas gingivalis through the sortase of its type IX secretion system.

  • Dr. F. Xavier Gomis Rüth
    Institut Biologia Molecular de Barcelona IBMB - CSIC
Fund: 195.500,00 €

Improvement of the microbiological methods associated with the treatment of chronic pulmonary infections by non-tuberculous mycobacteria.

  • Dr. Julià González Martín
    Institut de Salut Global de Barcelona - ISGLOBAL
Fund: 199.996,88 €

Clinical and microbiological impact of the new antipseudomonals ceftolozane-tazobactam and ceftazidime-avibactam in extremely resistant Pseudomonas aeruginosa infections.

  • Dr. Juan Pablo Horcajada Gallego
    Institut Mar d'Investigacions Mèdiques - IMIM
Fund: 196.625,00 €

A new approach to combat multiresistance to antibiotics: attacking antigen proteins coded by plasmids of antibiotic resistance.

  • Dr. Antonio Juárez Giménez
    Facultat de Biologia. Universitat de Barcelona
Fund: 196.250,00 €

Subclinical infections in childhood and their impact on health.

  • Dr. Emmanouil Kogevinas
    Institut de Salut Global de Barcelona - ISGLOBAL
Fund: 199.875,00 €

Effectiveness and cost-effectiveness of improving physicians’ diagnostic and communicative skills in the adaptation of the antibiotherapy in patients with acute cough in primary care in Catalonia.

  • Dr. Carles Llor Vilà
    Institut d'Investigació en Atenció Primària Jordi Gol - IDIAP
  • Dra. Marta Trapero Bertran
    Institut de Recerca d'Avaluació i polítiques Públiques – IRAPP. Universitat Internacional de Catalunya
  • Dr. Antoni Sisó Almirall
    Fundació d'Atenció Primària de Barcelona
Fund: 377.375,00 €

Evaluation of the public health risk of the atypical and emerging prions.

  • Dr. Francesc Josep Llorens Torres
    Institut d'Investigació Biomèdica de Bellvitge IDIBELL - CIBER
  • Dr. Juan Carlos Espinosa Martín
    Centro de Investigación en Sanidad Animal CISA - INIA
  • Dr. Enric Vidal Barba
    Institut de Recerca i Tecnologia Agroalimentàries – IRTA. Centre Recerca en Sanitat Animal - CRESA
Fund: 400.000,00 €

Extracellular traps of neutrophils and sepsis: clinical implications in kidney transplant.

  • Dr. José Miguel López-Botet Arbona
    Institut Mar d'Investigacions Mèdiques - IMIM
Fund: 196.875,00 €

Trampes extracel·lulars de neutròfils i sèpsia: discovery of diagnostic and prognostic markers, and therapeutic targets.

  • Dr. Joaquín López-Contreras González
    Institut de Recerca Hospital de la Santa Creu i Sant Pau
Fund: 156.875,00 €

Evaluation of new mutations of cytomegalovirus in the transplant patient suspected of resistance to antivirals through phenotype assay.

  • Dra. M. Angeles Marcos Maeso
    Institut de Salut Global de Barcelona - ISGLOBAL
Fund: 165.951,25 €

Use of quorum sensing signalling molecules as tools for the diagnosis of bacterial infections.

  • Dra. Maria Teresa Martín Gómez
    Institut de Recerca Hospital Universitari Vall d'Hebron VHIR
  • Dra. M. Pilar Marco Colás
    Institut de Química Avançada de Catalunya CSIC
Fund: 227.684,84 €

Pilot project for screening of Chagas disease in community pharmacies.

  • Dra. Inés Oliveira Souto
    Institut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: 121.150,00 €

Dietary improvement of the anti-infectious components of human milk as a tool for controlling infections in early stages of life (DIM-2-ELI).

  • Dr. Francisco José Pérez Cano
    Facultat de Farmàcia i Ciències de l'Alimentació. Universitat de Barcelona
  • Dra. M. Carmen Collado
    Instituto de Agroquímica y Tecnología de Alimentos Burjassot - CSIC
Fund: 298.812,50 €

Pseudoenveloped virus particles in exosome candidates for new vaccines for hepatitis A and E.

  • Dra. Rosa Maria Pintó Solé
    Facultat de Biologia. Universitat de Barcelona
  • Dra. Margarida Castell Escuer
    Facultat de Farmàcia i Ciències de l'Alimentació. Fundació Bosch i Gimpera. Universitat de Barcelona
  • Dr. Fernando Rodríguez González
    Institut de Recerca i Tecnologia Agroalimentàries – IRTA. Centre Recerca en Sanitat Animal - CRESA
Fund: 399.375,00 €

New polymyxins for the treatment of infections caused by multiresistant bacteria.

  • Dr. Francesc Rabanal Anglada
    Facultat de Química. Universitat de Barcelona
Fund: 200.000,00 €

Study of the reversions of an interferon-γ release test (QuantiFERON-TB Gold Plus) in the study of tuberculosis contacts.

  • Dr. Miguel Santín Cerezales
    Institut d'Investigació Biomèdica de Bellvitge - IDIBELL
Fund: 83.473,75 €

Pulmonary and cardiac lesions caused by severe pneumococcal pneumonia: assessment of the effect of corticoids and macrolides in an animal model.

  • Dr. Antoni Torres Martí
    Institut d'Investigació Biomèdica August Pi i Sunyer - IDIBAPS
Fund: 200.000,00 €

Discovery of innovative drugs against viral respiratory infections.

  • Dr. Santiago Vázquez Cruz
    Facultat de Farmàcia i Ciències de l'Alimentació. Universitat de Barcelona
  • Dra. Lieve Naesens
    Rega Institute for Medical Research - University of Leuven. Bèlgica
Fund: 279.791,52 €

From structure to mechanisms by which the Zika virus causes congenital neuropathy.

  • Dra. Núria Verdaguer Massana
    Institut Biologia Molecular de Barcelona IBMB - CSIC
Fund: 200.000,00 €

Design and development of a chimerical molecule for the treatment of infections caused by microorganisms multiresistant to antibiotics.

  • Dr. Jordi Vila Estapé
    Institut de Salut Global de Barcelona - ISGLOBAL
  • Dr. Ernest Giralt Lledó
    Institut de Recerca Biomèdica - Parc Científic de Barcelona
Fund: 260.000,00 €

Breaking frown the boundaries of resistance to antimicrobials; seeking new antimicrobials against multiresistant bacteria: a work on polycationic peptides and lipid nanoparticles (BARNAPA).

  • Dr. Miquel Viñas Ciordia
    Facultat de Medicina. Universitat de Barcelona
  • Dr. Fernando Albericio Palomera
    School of Chemistry and Physics. University of KwaZulu-Natal. Sud-àfrica
  • Dra. Stefania Stefani
    LMMAR lab - University of Catania
Fund: 383.276,25 €

Platform for training, auditing and feedback in sepsis for improved implementation of the sepsis code.

  • Dr. Juan Carlos Yébenes Reyes
    Hospital de Mataró - Consorci Sanitari del Maresme
Fund: 195.625,00 €