FUNDED PROJECTS:
CANCER

cartell MaratóIn 1994 La Marató de TV3 raised money for cancer, with € 2,821,752 distributed to 60 biomedical research projects. The results were published in the I Simposium Fundació La Marató de TV3, which took place in 2000.
Below is a list of the projects financed by La Marató in 1994. Those that led to the production of scientific literature are underlined.

Genetic Bases of Family Aggregation in Colorectal tumors

  • Dra. Montserrat Andreu García
    Hospital del Mar
Fund: 6.010 €

Molecular Mechanisms Involved in the Process of Cachexy Associated with a Tumor of the Colon

  • Dr. Josep M Argilés Huguet
    Facultat de Biologia. Universitat de Barcelona
Fund: 30.051 €

Human Genetics: Regulation of Oncogenes with a Large Presence in Tumors by Constitutive Modulating Factors of Genetic Expression

  • Dra. Montserrat Bach Elías
    Centre d'Investigació i Desenvolupament. CSIC
Fund: 21.035 €

Genome Instability and Colorectal Cancer

  • Dr. Oriol Bachs Valldeneu
    Unitat d'Investigació Mixta. Hospital Clínic i Provincial de Barcelona
Fund: 66.111 €

Molecular Study of the Genes BRCA1 and BRCA2 in Breast Cancer and/or Hereditary Ovarian Cancer

  • Dra. Montserrat Baiget Bastus
    Hospital de la Santa Creu i Sant Pau
Fund: 120.202 €

Analysis of in vitro and in vivo Radiosensitivity in Human Colon Tumoral Cells and Their Modulation by Phase S Specific Cytostatics

  • Dr. Josep Balart Serra
    Hospital de la Santa Creu i Sant Pau
Fund: 12.020 €

Role of Oncogens (p53 retinoblastoma and mdm2) in Malignant change and in Establishing Prognosis in Patients with Colon and Rectal Neoplasms

  • Dr. Antoni M Ballesta Gimeno
    Hospital Clínic i Provincial de Barcelona
Fund: 24.040 €

Inhibiting the Proliferation of Cells Derived from Colon Cancer by Cyclooxygenase Inhibitors

  • Dr. Ramon Bartrons Bach
    Facultat d'Odontologia Universitat de Barcelona
Fund: 54.091 €

Cell Differentiation and Metastasis

  • Dr. Jerónimo Blanco Fernández
    Hospital Duran i Reynals
Fund: 90.152 €

Mechanisms of Progression/Invasion of Colorectal Cancer (Molecules of Adhesion Degradation of the Extracellular matrix) in Relation to the Main Genetic Paths of Neoplasm Transformation (ras/p53 Mutations and Genetic Instability)

  • Dr. Elias Campo Güerri
    Hospital Clínic i Provincial de Barcelona
Fund: 96.162 €

Genome Instability and Colorectal Cancer

  • Dr. Gabriel Capellà Munar
    Hospital de la Santa Creu i Sant Pau
Fund: 120.202 €

Alterations of the Suppression of Glycolytic Enzyme Genes in Breast Cancer

  • Dr. Josep Carreras Barnés
    Hospital Clínic i Provincial de Barcelona
Fund: 12.020 €

Genetic and Molecular Analysis of Oncogene Homologues and Tumor Suppressor Genes in Drosophila

  • Dr. Jordi Casanova Roca
    Centre d'Investigació i Desenvolupament. CSIC
Fund: 36.061 €

Detection of Neoplasm Cells by Determining mRNA Codified by Proteins Specific to Cells Originating in the Colon

  • Dr. Antoni Castells i Garangou
    Hospital Clínic i Provincial de Barcelona
Fund: 57.096 €

Induction of Neoplasms with PU.1. (Transcription factor) and hck (Tyrosine Kinase) Oncogenes

  • Dr. Antonio Celada Cotarelo
    Facultat de Biologia. Universitat de Barcelona
Fund: 24.040 €

Angiogenesis in Mechanisms of Tumoral Progression of Colon Cancer

  • Dra. M. Cinta Cid Xutglà
    Hospital Clínic i Provincial de Barcelona
Fund: 24.040 €

Molecular Study of Ocular Cancer in Infants: retinoblastoma

  • Dra. M. Dolors Coll Sandiumenge
    Facultat de Ciències. Universitat Autònoma de Barcelona
Fund: 16.828 €

Expression of Genes Regulating the Cellular Cycle during the Process of Programmed Cellular Death

  • Dr. Joan Xavier Comella Carnicé
    Facultat de Medicina. Universitat de Lleida
Fund: 36.061 €

Molecular Alterations of the Mechanisms of Membrane Glycosyl Traffic and Proteoglycans in Tumoral Progression of Colon and Breast Cancers

  • Dr. Gustavo Egea Guri
    Facultat de Medicina. Universitat de Barcelona
Fund: 33.056 €

Molecular Pathology of the Genes Inhibiting Kinases of the Cyclines in Malignant Melanoma and Research of Genes of Predisposition and Tumoral Progression in 9p21

  • Dr. Xavier Estivill Pallejà
    Fundació August Pi i Sunyer
Fund: 84.142 €

Genes Involved in Metastasis in Breast Cancer

  • Dra. Àngels Fabra Fres
    Fundació Institut de Recerca Oncològica
Fund: 102.172 €

Analysis of the Expression of Sub-Types of Bombesin Receptors in Colorectal Cancer

  • Dr. Antonio Farré Viladrich
    Hospital de la Santa Creu i Sant Pau
Fund: 30.051 €

Clonicity and Expression of the Plasminogen Receptor: Functional Characterization of its Action in Tumor Dissemination

  • Dr. Jordi Félez Brugués
    Hospital Duran i Reynals
Fund: 48.081 €

Study of the Alterations of Genes Regulating the Cellular Cycle (Cycline D1 RBp p16 p21 p53 and bcl-2) in Mammary Carcinomas: Biological Meaning and Clinical-Therapeutic Use

  • Dr. Pedro Luis Fernández Ruiz
    Hospital Clínic i Provincial de Barcelona
Fund: 21.035 €

Gene Expression in the External Germinal (Granular) Layer of the Brain as a Model of Regulating Cell Survival and Apoptosis in Neoproliferative Syndromes

  • Dr. Isidro Ferrer Abizanda
    Unitat Docent Bellvitge. Universitat de Barcelona
Fund: 85.945 €

Gene Therapy Strategies with Viral Vectors Using the Model of Human Exocrine Pancreatic Cancer

  • Dra. Cristina Fillat Fonts
    Fundació August Pi i Sunyer
Fund: 48.081 €

Study of the Clinical and Biological Prognosis Factors in Localized Infiltrating Carcinoma of the Bladder Treated with Neo-Adjuvant Chemotherapy and Radiotherapy or Cystectomy

  • Dr. José Ramón Germá Lluch
    Hospital Duran i Reynals
Fund: 30.051 €

Strategies of Gene Therapy with Virus Vectors Using the Model of Human Exocrine Pancreatic Cancer

  • Dra. Anna M Gómez-Foix
    Facultat de Química. Universitat de Barcelona
Fund: 12.020 €

Study of Randomization Treatment with Interleukin-2 in Patients with Follicular or Mantel Lymphoma about to undergo Bone Marrow Transplant or Purified Peripheral Precursors

  • Dr. Alberto Grañena Batista
    Ciutat Sanitària de Bellvitge
Fund: 72.121 €

Construction of Gene Libraries of cDNA of CD44 of Breast Duct Carcinomas for Characterizing the Exonic Composition of CD44 Isoforms Expressed in the Infiltrating and Metastatic Ganglion in situ Phases of these Tumors

  • Dr. Marc Isamat Riviere
    Hospital Universitari Germans Trias i Pujol
Fund: 18.030 €

Mutations of the NF1 and NF2 Genes in Neurological Tumors and Familiar Neurofibromatosis

  • Dra. Conxita Lázaro García
    Hospital Clínic i Provincial de Barcelona
Fund: 30.051 €

Molecular Mechanisms of Carcinogenesis in Testers and Relatives with High Risk of Endocrine Neoplasms: men-1 and men-2 Syndromes and Thyroid Tumors

  • Dr. Alberto de Leiva Hidalgo
    Hospital de la Santa Creu i Sant Pau
Fund: 60.101 €

Determining Genetic Alterations of Chromosome 17 with the FISH Technique in Breast Carcinoma

  • Dra. Belen Lloveras Rubio
    Ciutat Sanitària de Bellvitge
Fund: 39.066 €

Genetic Bases of Family Aggregation in Colorectal tumors

  • Dr. Fèlix Lluís Casajuana
    Hospital de la Santa Creu i Sant Pau
Fund: 120.202 €

Gene Therapy Strategies with Virual Vectors Using the Model of Human Exocrine Pancreatic Cancer

  • Dra. Adela Mazo Sánchez
    Facultat de Química. Universitat de Barcelona
Fund: 12.020 €

Identifying the Genes Involved in Neoplasm Transformation of Renal Cancer

  • Dra. Anna Meseguer Navarro
    Hospital Materno-infantil de la Vall d'Hebron
Fund: 36.061 €

Function of p53 Protein in Inhibiting Transcription

  • Dr. Cristóbal Mezquita Pla
    Facultat de Medicina. Universitat de Barcelona
Fund: 48.081 €

Genome Instability and Colorectal Cancer

  • Dra. Rosa Miró Ametller
    Facultat de Medicina. Universitat Autònoma de Barcelona
Fund: 36.061 €

Oncògens supressors (p53 retinoblastoma) mdm2 i HER-2/neu en la transformació maligna i pronòstic de les neoplàsies mamàries: relació amb factors associats a la quimioresistència (topoisomerasa II GST i glicoproteïna P

  • Dr. Rafael Molina Porto
    Hospital Clínic i Provincial de Barcelona
Fund: 24.040 €

Genetic Bases of Family Aggregation in Colorectal tumors

  • Dra. Josefina Mora Brugués
    Institut de Recerca. Hospital de la Santa Creu i Sant Pau
Fund: 30.051 €

Study of Randomization Treatment with Interleukin-2 in Patients with Follicular or Mantel Lymphoma Put under Bone Marrow Transplant or Purified Peripheral Precursors

  • Dr. Víctor Moreno Aguado
    Hospital Duran i Reynals
Fund: 107.581 €

Expression of Molecules Related to Invasion in Breast Cancer: Study in Human Intraductal and Microinfiltrating Carcinomas in Transfecting Lines from Culture and in Laboratory Animals

  • Dr. Abelardo Moreno Carazo
    Ciutat Sanitària i Universitària de Bellvitge
Fund: 93.157 €

Expression of Mitogenic Growth Factors and Inhibitors in Relation to Mutations of the Suppressor Genes BRCA1 and BRCA2 in Breast Cancer

  • Dr. Ángel Navarro Moreno Miguel
    Ciutat Sanitària i Universitària de Bellvitge
Fund: 30.051 €

Genetic Bases of Family Aggregation in Colorectal tumors

  • Dr. Antoni Obrador Adrover
    Hospital Son Dureta. Palma de Mallorca
Fund: 12.020 €

Nucleoprotein Structure of the Promoting Region and Control of the Expression of Gene hMSH2

  • Dr. Rafael Oliva Virgili
    Hospital Clínic i Provincial de Barcelona
Fund: 24.040 €

Cell Differentiation and Metastasis

  • Dra. Rosanna Paciucci
    Institut Municipal d'Assistència Sanitària
Fund: 21.035 €

Molecular Study of the Differential Expression of Nucleoside Transporters in Normal and Transformed Cells. Basis for Early Diagnosis of Hepatocellular Carcinoma and for Future Design of Anti-Tumor Drugs

  • Dr. Marçal Pastor Anglada
    Facultat de Biologia. Universitat de Barcelona
Fund: 36.061 €

Genome Instability and Colorectal Cancer

  • Dr. Miguel A. Peinado Morales
    Hospital Duran i Reynals
Fund: 96.162 €

Involvement of TGF-ALPHA and EGF-R in Tumor Progression of Human Colon Carcinomas

  • Dr. Ricardo Pérez Tomás
    Facultat d'Odontologia. Universitat de Barcelona
Fund: 18.030 €

Pathogenesis and Progression of Ovarian Cancer: Instability of Microsatellites and Molecular Alterations of Chromosome 17q (Allelic Losses and Expression of the Gene nm23)

  • Dr. Jaime Prat Díaz de Losada
    Hospital de la Santa Creu i Sant Pau
Fund: 60.101 €

Molecular and Cell Analysis of the Genes Involved in Developing Colon Cancer Using in vitro and in vivo Models

  • Dr. Francisco J. Real Arribas
    Institut Municipal d'Assistència Sanitària
Fund: 90.152 €

Mutations in Suppressor Genes BRCA1 and BRCA2 in Family and Sporadic Breast Cancer

  • Dra. Francisca Rivera Fillat
    Hospital Clínic i Provincial de Barcelona
Fund: 18.030 €

Isolating and Genetically and Functionally Characterizing the Cyclines in Neoblasts (Undifferentiated Stem Cells)

  • Dr. Emili Saló Boix
    Facultat de Biologia. Universitat de Barcelona
Fund: 12.020 €

BRCA1 and family relationship in Breast Cancer among Young Women. An International Study of Genetic Epidemiology

  • Dra. Sílvia de Sanjosé Llongueras
    Hospital Duran i Reynals
Fund: 34.859 €

Inhibiting Metastasis apoptosis in Breast Cancer

  • Dra. Àngels Sierra Jiménez
    Hospital Duran i Reynals
Fund: 108.182 €

Detecting the Gene GSTM1 and Risk of Colon Cancer Genetic Over-Expression of the GST Family in Tumor Cells

  • Dr. Manuel Trias Folch
    Hospital Clínic i Provincial de Barcelona
Fund: 24.040 €

Molecular Alterations of the Mechanisms of Membrane Glycosyl Traffic and Proteoglycans in Tumoral Progression of Colon and Breast Cancers

  • Dr. Senén Vilaró Coma
    Facultat de Biologia. Universitat de Barcelona
Fund: 27.046 €

Involvement of ETS Oncoproteins in Mammary Neoplasm Transformation

  • Dr. Francesc Villarroya Gombau
    Facultat de Biologia. Universitat de Barcelona
Fund: 10.217 €

PCR Detection of Residual Minimal Disease in the Breast. Significant Prognosis

  • Dra. Núria Viñolas Segarra
    Hospital Clínic i Provincial de Barcelona
Fund: 24.040 €

Action Regulating the Oncogene mdm-2 over the Antioncogene p53. Involvement of c-myc in this Regulation

  • Dr. Jordi Vives Puiggros
    Fundació Clínic per a la Recerca Biomèdica. Hospital Clínic i Provincial de Barcelona
Fund: 108.182 €
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