FUNDED PROJECTS:
AIDS
In 2001 the Marathon, which was dedicated to Aids, received 107 project applications; these were evaluated by 49 scientists specialising in HIV around the world who drew up an order of priority depending on the methodological quality and relevance of the project. The assessment was managed by the Catalan Agency for Health Technology Assessment and Research.
In accordance with the proposal from the Advisory Committee of the Fundació La Marató de 3Cat, the Board agreed to distribute, after paying the costs of the evaluation, € 3,910,600 to 21 biomedical research projects. The results were published in the VIII Simposium Fundació La Marató de 3Cat, which took place in 2007.
State epidemiological information system on non-occupational HIV post-exposure prophylaxis. Study of viability and effectiveness of post-exposure prophylaxis in the non-health field
- Dr. Jesús Almeda OrtegaHospital Universitari Germans Trias i Pujol
Fund: 146.686 €
Epidemiological quantification and characterisation of HIV seroconversors using the Serological Testing Algorithm for Recent HIV Seroconversion (STARHS) technique.
- Dr. Jordi Casabona BarbaràHospital Universitari Germans Trias i Pujol
Fund: 176.088 €
Entry of the immunodeficiency virus to the target cell and physiochemical characteristics of the cell membrane: importance of the dipolar membrane potential and of the proteglycans of the cell surface
- Dr. Josep B. Cladera CerdàFacultat de Medicina / UAB
Fund: 90.457 €
Analysis of the prevalence of HIV resistant to antiretrovirals and subtypes in patients with no previous experience of antiviral treatment in Spain
- Dr. Bonaventura Clotet SalaHospital Universitari Germans Trias i Pujol
- Dr. Santiago Moreno GuillenHospital Ramon y Cajal / Madrid
- Dr. Vicente Soriano VázquezInstituto de Salud Carlos III / Madrid
- Dra. Nuria Margall CoscojuelaHospital de la Santa Creu i Sant Pau
- Dra. Asunción Moreno CamachoHospital Clínic i Provincial de Barcelona
Fund: 193.229 €
Redirection of T-cells specificity against HIV epitopes restricted by HLA-A2 using gene transfer
- Dr. Oscar de la Calle MartinHospital de la Santa Creu i Sant Pau
Fund: 166.120 €
Molecular bases of lipodystrophy associated with high-activity antiretroviral therapy in Aids patients: a genomic approach
- Dr. Pere Domingo PedrolFacultat de Medicina / UAB
- Dra. Marta Giralt OmsFacultat de Biologia / UB
Fund: 176.000 €
Design, synthesis, and evaluation of the antiviral activity of new anti-HIV compounds
- Dr. José Andrés Esté AraqueFundació irsiCaixa / HUGTiP
- Dr. Jordi Teixidó ClosaGrup d'Enginyeria Molecular / IQS
- Dra. Josefa Mallol MonteroFacultat de Química / UB
Fund: 309.336 €
Genetic variability of the locus of the vitamin D receptor (VDR) and progression of HIV infection. Study of new variants and characterisation of the molecular base of the differential progression to Aids conferred by VDR polymorphisms
- Dr. Joan Fibla PalazónFacultat de Medicina / UdL
- Dra. Montserrat Plana PradesHospital Clínic i Provincial de Barcelona
- Dr. Antonio José Caruz ArcosFacultad de Ciencias Experimentales / UJ
- Dr. Benito Regueiro GarciaUniversidad de Santiago / Sergas
Fund: 359.191 €
The role of CXCR4/CD26 heteromers in the T-lymphocyte functionality and in the entry and infectiveness of HIV.
- Dr. Rafael Franco FernándezFacultat de Química / UB
Fund: 180.028 €
Use of autologous myeloid dendrite cells as a cellular adjuvant for a therapeutic vaccine against the type-1 immunodeficiency virus (HIV-1) in infected patients in primary stages of the disease receiving high-activity antiretroviral treatment
- Dr. Josep M. Gatell ArtigasHospital Clínic i Provincial de Barcelona
Fund: 169.560 €
Polymorphic receptors of the innate immune system (MBL, TLR) and susceptibility to bacterial infections in patients infected by HIV: a study of cases and controls
- Dr. Juan Pablo Horcajada GallegoHospital Clínic i Provincial de Barcelona
Fund: 111.600 €
Lethal mutagenesis, a new antiviral strategy
- Dr. Miguel Angel Martínez de la SierraFundació irsiCaixa / HUGTiP
Fund: 154.349 €
Molecular and cellular immunity in identical twins, infected by the same stem of the human immunodeficiency virus (HIV-1)
- Dr. Xavier Martínez PicadoHospital Universitari Germans Trias i Pujol
Fund: 147.124 €
Phenotype and molecular characterisation of the non-Hodgkin's lymphomas associated with Aids using tissue microarray techniques
- Dr. José Luis Mate SanzHospital Universitari Germans Trias i Pujol
Fund: 174.118 €
Analysis of the function of the mitochondrial respiratory chain in patients infected by HIV who develop hyperlactataemia during antiretroviral treatment
- Dr. Òscar Miró AndreuHospital Clínic i Provincial de Barcelona
Fund: 82.080 €
Long-term consequences of hepatitis C and B in intravenous drug addicts infected by HIV
- Dr. Robert Muga BustamanteHospital Universitari Germans Trias i Pujol
- Dr. Ildefonso Hernández AguadoFacultad de Medicina / UMH
Fund: 179.486 €
Inhibitor effect of the urokinase-receptor system in HIV-1 replication: in vitro and in vivo study
- Dra. Pura Muñoz CánovesCentre de Regulació Genòmica
- Dr. Guido PoliHospital San Raffaele Scientific Institute / Milano
- Dr. Francesco BlasiFaculty of Medicine / Milano
Fund: 359.772 €
Invasive pneumococcal disease in patients infected by the of human immunodeficiency virus. Multi-centre study of three European hospitals
- Dr. Romà Pallarés GinerCiutat Sanitària i Universitària de Bellvitge
Fund: 179.099 €
Regulatory mechanisms of adipogenesis to HIV-associated lipodystrophy
- Dr. Cristóbal Richart JuradoHospital Universitari Joan XXIII / Tarragona
Fund: 99.907 €
Identification of the cell factors that interact with the Vif protein of the acquired immunodeficiency virus
- Dr. Juan Sayós OrtegaFacultat de Ciències de la Salut i de la Vida / UPF
Fund: 142.549 €
Polymorphism of rant and SDF-1 chemokines and their influence on virological response and immunological recovery due to antiretroviral treatment in patients infected by HIV.
- Dr. Francesc Vidal MarsalFacultat de Medicina / URV
- Dr. Hernando Knobel FreudHospital del Mar
- Dr. Juan Antonio Arroyo DíazHospital de la Santa Creu i Sant Pau
- Dr. Santiago Montull MorerHospital General de Granollers
- Dr. David Dalmau JuanolaHospital Mútua de Terrassa
Fund: 313.821 €