FUNDED PROJECTS:
NEUROLOGICAL DISEASES

All funded projects

cartell Marató Following the 1996 edition, which was dedicated to neurological diseases, the sum of €3,677,019 was distributed among the 37 biomedical researh projects listed below and used to support research on these diseases. The results were published in the III Simposium Fundació La Marató de 3Cat, which took place in 2002.
Below is a list of the projects financed by La Marató in 1996. Those that led to the production of scientific literature are underlined.

Study on Alzheimer's Disease in Primary Care: Follow-Up of a Host of People over 65 and Evaluation of the Effectiveness of Support Intervention for the Primary Carers of these Patients

Dr. Josep M. Argimon Pallàs
Fundació Jordi Gol i Gurina

Fund: 34.763 €

JC Virus and Glial Cells: Study of Deregulation of the Cell Cycle in Progressive Multifocal Leuko-Encephalopathy

Dr. Aurelio Ariza Fernández
Hospital Universitari Germans Trias i Pujol

Fund: 63.707 €

Role of Adamalycins in Generating the Abeta Peptide

Dr. Joaquín Arribas López
Hospital General Universitari Vall d'Hebron

Fund: 94.240 €

Design, Synthesis and Pharmacological Evaluation of Analogues of Huperzina A as Anti-Cholinesterase with Potential Use in Treating Alzheimer's Disease

Dr. Pelayo Camps García
Facultat de Farmacia. Universitat de Barcelona
Dr. Albert Badia Sancho
Facultat de Medicina. Universitat Autònoma de Barcelona
Dr. Francisco Javier Luque Garriga
Facultat de Farmàcia. Universitat Autònoma de Barcelona

Fund: 143.341 €

Can Glial Cells Determine Survival or Neuron Death during Evolution of Neuro-Degenerative Processes?

Dr. Bernardo Castellano López
Facultat de Medicina. Universitat Autònoma de Barcelona

Fund: 110.088,59 €

Genetic and Physio-Pathological Neuro-Pathological Correlations in Alzheimer's Disease: Characterization of a Peripheral Model for Diagnosis and Experimental Handling of the Disease

Dr. Félix Francisco Cruz-Sánchez
Universitat Internacional de Catalunya
Dra. Arantxa Ortega Aznar
Hospital General Universitari Vall d'Hebron
Dr. José Luis Mate Sanz
Hospital Universitari Germans Trias i Pujol

Fund: 319.726 €

Excitotoxic Mechanisms in the Spinal Motoneuron and Its Implications in the Pathogeny of Amyotrophic Lateral Sclerosis

Dr. Josep-Enric Esquerda Colell
Facultat de Medicina. Universitat de Lleida

Fund: 139.718 €

Involvement of Apoptosis Proteins, Calcium-Binding Proteins and Trophic Factors in Human Neuro-Degenerative Diseases and in Experimental in vivo and in vitro Models

Dr. Isidre Ferrer Abizanda
Ciutat Sanitària i Universitària de Bellvitge

Fund: 81.055 €

AnàlisiImmuno-Histologic and Genetic Clinical Analysis of Dystrophy of the Waist

Dra. Maria Pia Gallano Petit
Hospital de la Santa Creu i Sant Pau

Fund: 50.317 €

Effect of Inflammatory Cytokines on the Cyclical Nitric Oxide /GMP System of Nerve Cells in Relation to Multiple Sclerosis and Alzheimer's Disease

Dra. M. C. Agustina García Sánchez
Institut de Biologia Fonamental Vicent Villar i Palasí. Universitat Autònoma de Barcelona

Fund: 77.350 €

Prospective Neuro-Psychological Neuro-Physical and Spectroscopic Study of Early Markers of Alzheimer's Disease

Dra. Carmen García Sánchez
Hospital de la Santa Creu i Sant Pau

Fund: 65.253 €

Specificity and Pathogenic Value of Glucolipidic Antigens in Motor Neurons: Relevance in ALS and Other Motor Syndromes

Dr. Josep Maria Grau Veciana
Hospital de la Santa Creu i Sant Pau
Dra. Francisca Vidal Domínguez
Facultat de Veterinària. Universitat Autònoma de Barcelona
Dr. Nicolau Ortiz Castellon
Facultat de Medicina. Universitat Rovira i Virgili

Fund: 297.987 €

Multiple Sclerosis and Paraneoplastic Encephalomyelitis

Dr. Francesc Graus Ribas
Hospital Clínic i Provincial de Barcelona

Fund: 161.732 €

Study and Characterization of Specific T anti-GAD Cells in Patients with Auto-Immune Cerebellar Ataxia and Stiff-Man Syndrome. Comparison with Insulin-Dependent Diabetes Mellitus

Dra. Dolores Jaraquemada Pérez de Guzman
Facultat de Medicina. Universitat Autònoma de Barcelona

Fund: 85.428 €

Evaluation of the Efficiency, Safety and Effectiveness of Multiple Sclerosis Treatment and Impacts on the Quality of Life of Patients and their Relatives

Dr. Albert J. Jovell Fernández
Agència d'Avaluació de Tecnologia i Recerca Mediques

Fund: 57.570 €

Longitudinal Study of the Functional Reorganization of Frontal Basal Ganglion Circuits Following Pallidotomy or Posteroventral Pallial Electric Stimulation Guided by Microregister for Surgical Treatment

Dr. Jaume Kulisevsky Bojarski
Hospital de la Santa Creu i Sant Pau

Fund: 60.339 €

Depressive Disorders in Patients Affected by Essential Thrombocythemia. Study of the Possible Serotoninergic Mechanisms Involved

Dr. Miquel Marco Igual / Dr. Josep Mª Ribera Santasusana
Consorci Hospitalari Parc Taulí. Sabadell / Hospital Universitari Germans Trias i Pujol

Fund: 46.452 €

Comparative Analysis of the Pathogeny of Leucoaraiosis between Binswanger's Disease and Alzheimer's Disease: Haemodynamic Haemorrheological Studies of Conventional and Spectroscopic Magnetic Resonance

Dr. Joan Martí Fàbregas
Hospital de la Santa Creu i Sant Pau

Fund: 53.950 €

Interactions among Glutamate, Dopamine, Polyamines and Adenosine in Neuro-Degenerative Processes. An Experimental Approach to Parkinson's Disease

Dr. Emili Martínez Hermida
Institut d'Investigacions Biomèdiques de Barcelona. CSIC

Fund: 59.095 €

Inflammatory Mechanisms in the Pathogenesis of Alzheimer's Disease: Study of the Role of Phosphodiesterases

Dra. Guadalupe Mengod Los Arcos
Instituto de Investigaciones Biomédicas de Barcelona. CSIC

Fund: 162.273 €

Identification and Study Using Combinatorial Libraries of New Therapeutic Agents Related to Inhibiting Acetyl-Cholinesterase and to the Neuro-Toxicity of Glutamate

Dr. Àngel Messeguer Peipoch
Centre d'Investigació i Desenvolupament. CSIC
Dr. Vicente Felipo Orts
Institut d'Investigacions Citològiques. Fundació Valenciana d'Investigacions Biomèdiques

Fund: 162.273 €

Role of the Proteolytic Enzyme tPA in Neuron Migration during the Development of the Cerebellum in Mice with tPA deficiencies (tPA -/-). Transcriptional Regulation of the tPA by Thyroid Hormone in the Central Nervous System

Dra. Pura Muñoz Cánoves
Institut d'Investigació Oncològica

Fund: 115.220 €

Is There a Correlation between Mutations in the +Subunits of Complexes of the Respiratory Chain Coded by Mitochondrial DNA (mtDNA) and its Enzyme Activity in Patients Suffering from Alzheimer's Disease?

Dra. Virginia Nunes Martínez
Centre de Genètica Mèdica i Molecular. Institut d'Investigació Oncològica
Dr. Jordi Casademont Pou
Hospital Clínic i Provincial de Barcelona

Fund: 124.019 €

Computer-Assisted Design of Selective Agonists and Antagonists of Muscarinic Receptors as Treatment for Alzheimer's Disease

Dr. Leonardo Pardo Carrasco
Facultat de Medicina. Universitat Autònoma de Barcelona

Fund: 86.527 €

Circuits of the Rat and Human Cerebral Cortex that are Rich in Zinc: A Group of Glutamatergic Circuits with Possible Involvement in Epilepsy

Dr. Jeús Pérez Clausell
Facultat de Biologia. Universitat de Barcelona

Fund: 49.509 €

Recording and Analysis of Data on Amyotrophic Lateral Sclerosis (ALS) in Catalonia

Dr. Jesús Pradas Orozco
Hospital de la Santa Creu i Sant Pau

Fund: 43.002 €

Quantification of Selectivity in Re-Innervation of the Proximal and Distal Muscles of the Lower Extremity Following Lesion of the Sciatic Nerve

Dr. Alberto Prats Galino
Facultat de Medicina. Universitat de Barcelona

Fund: 23.638 €

Opiated Endogenous System: Modulation Inhibiting Sensory Transmission during Peripheral Inflammation

Dra. Margarita Puig Riera de Conías
Institut Municipal d'Investigació Mèdica
Dra. Eulalia Planas Domingo
Facultat d'Odontologia. Universitat de Barcelona

Fund: 144.243 €

Involvement of Central Tolerance in Auto-Immune Neurological Diseases

Dr. Ricardo Pujol Borrell
Hospital Universitari Germans Trias i Pujol

Fund: 111.033 €

Study of the Alterations of Cerebral Blood Flow and Tissue Oxygenation in Patients Having Severe Cranial-Encephalic Trauma and Diffused Post-Traumatic Lesions

Dr. Joan Sahuquillo Barris
Hospital de Traumatologia Vall d'Hebron

Fund: 40.530 €

Schizophrenia and Serotoninergic System. Therapeutic Implications

Dr. Lluís San Molina
Benito Menni Complex Assistencial en Salut Mental. Sant Boi de Llobregat

Fund: 12.568 €

Potential of the Netrina 1/DCC Signalling System in Regenerating CNS

Dr. Eduard Soriano García
Facultat de Biología. Universitat de Barcelona
Dra. Myriam Fabre
Institut Municipal d'Investigació Mèdica